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Lung-Restricted Macrophage Activation in the Pearl Mouse Model of Hermansky-Pudlak Syndrome()

Pulmonary inflammation, abnormalities in alveolar type II cell and macrophage morphology, and pulmonary fibrosis are features of Hermansky-Pudlak Syndrome (HPS). We used the naturally occurring “pearl” HPS2 mouse model to investigate the mechanisms of lung inflammation observed in HPS. Although base...

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Detalhes bibliográficos
Main Authors: Young, Lisa R., Borchers, Michael T., Allen, Holly L., Gibbons, Reta S., McCormack, Francis X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783655/
https://ncbi.nlm.nih.gov/pubmed/16547274
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