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Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome

Alveolar epithelial cell (AEC) dysfunction underlies the pathogenesis of pulmonary fibrosis in Hermansky-Pudlak syndrome (HPS) and other genetic syndromes associated with interstitial lung disease; however, mechanisms linking AEC dysfunction and fibrotic remodeling are incompletely understood. Since...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Young, Lisa R., Gulleman, Peter M., Short, Chelsi W., Tanjore, Harikrishna, Sherrill, Taylor, Qi, Aidong, McBride, Andrew P., Zaynagetdinov, Rinat, Benjamin, John T., Lawson, William E., Novitskiy, Sergey V., Blackwell, Timothy S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070955/
https://ncbi.nlm.nih.gov/pubmed/27777976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88947
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