Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1.

We have isolated and characterized human monoclonal antibody 2G12 to the gp120 surface glycoprotein of human immunodeficiency virus type 1 (HIV-1). This antibody potently and broadly neutralizes primary and T-cell line-adapted clade B strains of HIV-1 in a peripheral blood mononuclear cell-based ass...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Trkola, A, Purtscher, M, Muster, T, Ballaun, C, Buchacher, A, Sullivan, N, Srinivasan, K, Sodroski, J, Moore, J P, Katinger, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8551569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.2.1100-1108.1996
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