A broadly neutralizing monoclonal antibody that recognizes the V3 region of human immunodeficiency virus type 1 glycoprotein gp120.

Previous studies have demonstrated that the principal neutralizing determinant of human immunodeficiency virus type 1 (HIV-1) is located in the V3 loop of glycoprotein gp120. Antibodies prepared against this region using gp120 or peptides as immunogens have been predominantly HIV-1-isolate-specific....

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Detalhes bibliográficos
Main Authors: Ohno, T, Terada, M, Yoneda, Y, Shea, K W, Chambers, R F, Stroka, D M, Nakamura, M, Kufe, D W
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53003/
https://ncbi.nlm.nih.gov/pubmed/1961739
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