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Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.

A panel of anti-gp120 human monoclonal antibodies (HuMAbs), CD4-IgG, and sera from people infected with human immunodeficiency virus type 1 (HIV-1) was tested for neutralization of nine primary HIV-1 isolates, one molecularly cloned primary strain (JR-CSF), and two strains (IIIB and MN) adapted for...

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Udgivet i:J Virol
Principais autores: Moore, J P, Cao, Y, Qing, L, Sattentau, Q J, Pyati, J, Koduri, R, Robinson, J, Barbas, C F, Burton, D R, Ho, D D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7527081/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.1.101-109.1995
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