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Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.

A panel of anti-gp120 human monoclonal antibodies (HuMAbs), CD4-IgG, and sera from people infected with human immunodeficiency virus type 1 (HIV-1) was tested for neutralization of nine primary HIV-1 isolates, one molecularly cloned primary strain (JR-CSF), and two strains (IIIB and MN) adapted for...

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Bibliografiset tiedot
Päätekijät: Moore, J P, Cao, Y, Qing, L, Sattentau, Q J, Pyati, J, Koduri, R, Robinson, J, Barbas, C F, Burton, D R, Ho, D D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1995
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC188553/
https://ncbi.nlm.nih.gov/pubmed/7527081
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