Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1.

We have isolated and characterized human monoclonal antibody 2G12 to the gp120 surface glycoprotein of human immunodeficiency virus type 1 (HIV-1). This antibody potently and broadly neutralizes primary and T-cell line-adapted clade B strains of HIV-1 in a peripheral blood mononuclear cell-based ass...

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Bibliografske podrobnosti
Main Authors: Trkola, A, Purtscher, M, Muster, T, Ballaun, C, Buchacher, A, Sullivan, N, Srinivasan, K, Sodroski, J, Moore, J P, Katinger, H
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC189917/
https://ncbi.nlm.nih.gov/pubmed/8551569
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