Resistance of herpes simplex virus type 1 to peptidomimetic ribonucleotide reductase inhibitors: selection and characterization of mutant isolates.

Herpes simplex virus (HSV) encodes its own ribonucleotide reductase (RR), which provides the high levels of deoxynucleoside triphosphates required for viral DNA replication in infected cells. HSV RR is composed of two distinct subunits, R1 and R2, whose association is required for enzymatic activity...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Bonneau, A M, Kibler, P, White, P, Bousquet, C, Dansereau, N, Cordingley, M G
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189880/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8551616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.2.787-793.1996
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