Resistance of herpes simplex virus type 1 to peptidomimetic ribonucleotide reductase inhibitors: selection and characterization of mutant isolates.

Herpes simplex virus (HSV) encodes its own ribonucleotide reductase (RR), which provides the high levels of deoxynucleoside triphosphates required for viral DNA replication in infected cells. HSV RR is composed of two distinct subunits, R1 and R2, whose association is required for enzymatic activity...

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izdano v:	J Virol
Principais autores:	Bonneau, A M, Kibler, P, White, P, Bousquet, C, Dansereau, N, Cordingley, M G
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1996
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189880/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8551616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.2.787-793.1996
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