Antiviral Activity of a Selective Ribonucleotide Reductase Inhibitor against Acyclovir-Resistant Herpes Simplex Virus Type 1 In Vivo

The present study reports the activity of BILD 1633 SE against acyclovir (ACV)-resistant herpes simplex virus (HSV) infections in athymic nude (nu/nu) mice. BILD 1633 SE is a novel peptidomimetic inhibitor of HSV ribonucleotide reductase (RR). In vitro, it is more potent than ACV against several str...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Duan, Jianmin, Liuzzi, Michel, Paris, William, Lambert, Michelle, Lawetz, Carol, Moss, Neil, Jaramillo, Jorge, Gauthier, Jean, Déziel, Robert, Cordingley, Michael G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC105657/
https://ncbi.nlm.nih.gov/pubmed/9660995
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires