Emergence of virus escape mutants after immunization with epitope vaccine.

BALB/c and C57BL/6J mice were immunized with recombinant vaccines consisting of lymphocytic choriomeningitis virus CD8+ T-lymphocyte epitopes and a carrier protein. During challenge infection with WE strain lymphocytic choriomeningitis virus, mutants with alterations in distinct amino acid residues...

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Bibliografiske detaljer
Main Authors: Weidt, G, Deppert, W, Utermöhlen, O, Heukeshoven, J, Lehmann-Grube, F
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189635/
https://ncbi.nlm.nih.gov/pubmed/7474135
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