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Type 1 CD4(+) T-Cell Help Is Required for Induction of Antipeptide Multispecific Cytotoxic T Lymphocytes by a Lipopeptidic Vaccine in Rhesus Macaques

We have optimized the induction of antiviral cytotoxic T lymphocytes (CTL) in rhesus macaques by a lipopeptide vaccine containing seven peptides from simian immunodeficiency virus (SIV) Nef and Gag proteins and a strong T-helper peptide from tetanus toxoid (TT) that is promiscuous in humans (peptide...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Mortara, Lorenzo, Gras-Masse, Helene, Rommens, Corinne, Venet, Alain, Guillet, Jean-Gerard, Bourgault-Villada, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104228/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196344/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.4447-4451.1999
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