Type 1 CD4(+) T-Cell Help Is Required for Induction of Antipeptide Multispecific Cytotoxic T Lymphocytes by a Lipopeptidic Vaccine in Rhesus Macaques

We have optimized the induction of antiviral cytotoxic T lymphocytes (CTL) in rhesus macaques by a lipopeptide vaccine containing seven peptides from simian immunodeficiency virus (SIV) Nef and Gag proteins and a strong T-helper peptide from tetanus toxoid (TT) that is promiscuous in humans (peptide...

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Main Authors: Mortara, Lorenzo, Gras-Masse, Helene, Rommens, Corinne, Venet, Alain, Guillet, Jean-Gerard, Bourgault-Villada, Isabelle
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC104228/
https://ncbi.nlm.nih.gov/pubmed/10196344
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