Emergence of virus escape mutants after immunization with epitope vaccine.

BALB/c and C57BL/6J mice were immunized with recombinant vaccines consisting of lymphocytic choriomeningitis virus CD8+ T-lymphocyte epitopes and a carrier protein. During challenge infection with WE strain lymphocytic choriomeningitis virus, mutants with alterations in distinct amino acid residues...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Weidt, G, Deppert, W, Utermöhlen, O, Heukeshoven, J, Lehmann-Grube, F
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1995
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189635/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7474135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.11.7147-7151.1995
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