Frequent disruption of the Nf1 gene by a novel murine AIDS virus-related provirus in BXH-2 murine myeloid lymphomas.

Evi-2, a common site of viral integration in BXH-2 myeloid lymphomas, is located within a large intron of the Nf1 tumor suppressor gene. Viral integration at Evi-2 appears to induce disease by disrupting normal Nf1 expression. During our attempts to characterize the nature of the proviruses located...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Cho, B C, Shaughnessy, J D, Largaespada, D A, Bedigian, H G, Buchberg, A M, Jenkins, N A, Copeland, N G
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189634/
https://ncbi.nlm.nih.gov/pubmed/7474134
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker