Retroviral Integration at the Epi1 Locus Cooperates with Nf1 Gene Loss in the Progression to Acute Myeloid Leukemia

Juvenile myelomonocytic leukemia (JMML) is a disease that occurs in young children and is associated with a high mortality rate. In most patients, JMML has a progressive course leading to death by virtue of infection, bleeding, or progression to acute myeloid leukemia (AML). As it is known that chil...

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Detalhes bibliográficos
Main Authors: Blaydes, Susan M., Kogan, Scott C., Truong, Bao-Tran H., Gilbert, Debra J., Jenkins, Nancy A., Copeland, Neal G., Largaespada, David A., Brannan, Camilynn I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114510/
https://ncbi.nlm.nih.gov/pubmed/11533205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.19.9427-9434.2001
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