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Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency

Retroviral gene therapy can restore immunity to infants with X-linked severe combined immunodeficiency (XSCID) caused by mutations in the IL2RG gene encoding the common gamma chain (γc) of receptors for interleukins 2 (IL-2), −4, −7, −9, −15, and −21. We investigated the safety and efficacy of gene...

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Main Authors:	Chinen, Javier, Davis, Joie, De Ravin, Suk See, Hay, Beverly N., Hsu, Amy P., Linton, Gilda F., Naumann, Nora, Nomicos, Effie Y. H., Silvin, Christopher, Ulrick, Jean, Whiting-Theobald, Narda L., Malech, Harry L., Puck, Jennifer M.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society of Hematology 2007
נושאים:	Gene Therapy
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1896128/ https://ncbi.nlm.nih.gov/pubmed/17369490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-058933
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Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency

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