Correction of canine X-linked severe combined immunodeficiency by in vivo retroviral gene therapy

X-linked severe combined immunodeficiency (XSCID) is characterized by profound immunodeficiency and early mortality, the only potential cure being hematopoietic stem cell (HSC) transplantation or gene therapy. Current clinical gene therapy protocols targeting HSCs are based upon ex vivo gene transfe...

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Autori principali: Ravin, Suk See Ting–De, Kennedy, Douglas R., Naumann, Nora, Kennedy, Jeffrey S., Choi, Uimook, Hartnett, Brian J., Linton, Gilda F., Whiting-Theobald, Narda L., Moore, Peter F., Vernau, William, Malech, Harry L., Felsburg, Peter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Hematology 2006
Soggetti:
Gene Therapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895747/
https://ncbi.nlm.nih.gov/pubmed/16384923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-10-4057
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