Correction of canine X-linked severe combined immunodeficiency by in vivo retroviral gene therapy

X-linked severe combined immunodeficiency (XSCID) is characterized by profound immunodeficiency and early mortality, the only potential cure being hematopoietic stem cell (HSC) transplantation or gene therapy. Current clinical gene therapy protocols targeting HSCs are based upon ex vivo gene transfe...

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Hlavní autoři: Ravin, Suk See Ting–De, Kennedy, Douglas R., Naumann, Nora, Kennedy, Jeffrey S., Choi, Uimook, Hartnett, Brian J., Linton, Gilda F., Whiting-Theobald, Narda L., Moore, Peter F., Vernau, William, Malech, Harry L., Felsburg, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Hematology 2006
Témata:
Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895747/
https://ncbi.nlm.nih.gov/pubmed/16384923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-10-4057
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