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Vaccination regimens incorporating CpG-containing oligodeoxynucleotides and IL-2 generate antigen-specific antitumor immunity from T-cell populations undergoing homeostatic peripheral expansion after BMT

Development of CD8(+) T-cell responses targeting tumor-associated antigens after autologous stem cell transplantations (ASCTs) might eradicate residual tumor cells and decrease relapse rates. Because thymic function dramatically decreases with aging, T-cell reconstitution in the first year after ASC...

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Detalhes bibliográficos
Main Authors: Kochenderfer, James N., Simpson, Jessica L., Chien, Christopher D., Gress, Ronald E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896127/
https://ncbi.nlm.nih.gov/pubmed/17371943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-057935
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