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The in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation

The recruitment of tumor necrosis factor receptor–associated factors (TRAFs) 1, 2, 3, 5, and 6 to the CD40 cytoplasmic tail upon CD40 trimerization results in downstream signaling events that ultimately lead to CD40-dependent, thymus-dependent (TD) humoral immune responses. Previously, we have shown...

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Bibliografske podrobnosti
Main Authors: Lu, Li-Fan, Ahonen, Cory L., Lind, Evan F., Raman, Vanitha S., Cook, W. James, Lin, Ling-Li, Noelle, Randolph J.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896113/
https://ncbi.nlm.nih.gov/pubmed/17360936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-038414
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