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Evidence for mutation showers

Mutants in the Big Blue transgenic mouse system show spontaneous clustered multiple mutations with unexpectedly high frequency, consistent with chronocoordinate events. We tested the prediction that the multiple mutations seen within the lacI mutation target sometimes occur in the context of chronoc...

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Detalles Bibliográficos
Main Authors: Wang, Jicheng, Gonzalez, Kelly D., Scaringe, William A., Tsai, Kimberly, Liu, Ning, Gu, Dongqing, Li, Wenyan, Hill, Kathleen A., Sommer, Steve S.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895962/
https://ncbi.nlm.nih.gov/pubmed/17485671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610902104
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