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Somatic microindels in human cancer: the insertions are highly error-prone and derive from nearby but not adjacent sense and antisense templates

Somatic microindels (microdeletions with microinsertions) have been studied in normal mouse tissues using the Big Blue lacI transgenic mutation detection system. Here we analyze microindels in human cancers using an endogenous and transcribed gene, the TP53 gene. Microindel frequency, the enhancemen...

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Библиографические подробности
Главные авторы: Scaringe, William A., Li, Kai, Gu, Dongqing, Gonzalez, Kelly D., Chen, Zhenbin, Hill, Kathleen A., Sommer, Steve S.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722894/
https://ncbi.nlm.nih.gov/pubmed/18632684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn190
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