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Telomerase recognizes its template by using an adjacent RNA motif

Telomerase adds telomeric repeats to chromosome 3′ ends, forestalling the cellular senescence, apoptosis, and genomic instability that result from telomere loss caused by incomplete DNA replication. The telomerase ribonucleoprotein is dedicated to synthesis of tandem, simple-sequence repeats by virt...

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Detalhes bibliográficos
Main Authors: Miller, Michael C., Collins, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124446/
https://ncbi.nlm.nih.gov/pubmed/11997465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102024699
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