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Telomerase recognizes its template by using an adjacent RNA motif

Telomerase adds telomeric repeats to chromosome 3′ ends, forestalling the cellular senescence, apoptosis, and genomic instability that result from telomere loss caused by incomplete DNA replication. The telomerase ribonucleoprotein is dedicated to synthesis of tandem, simple-sequence repeats by virt...

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Autors principals: Miller, Michael C., Collins, Kathleen
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124446/
https://ncbi.nlm.nih.gov/pubmed/11997465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102024699
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