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Telomerase recognizes its template by using an adjacent RNA motif

Telomerase adds telomeric repeats to chromosome 3′ ends, forestalling the cellular senescence, apoptosis, and genomic instability that result from telomere loss caused by incomplete DNA replication. The telomerase ribonucleoprotein is dedicated to synthesis of tandem, simple-sequence repeats by virt...

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Bibliografische gegevens
Hoofdauteurs: Miller, Michael C., Collins, Kathleen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC124446/
https://ncbi.nlm.nih.gov/pubmed/11997465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102024699
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