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Telomerase recognizes its template by using an adjacent RNA motif

Telomerase adds telomeric repeats to chromosome 3′ ends, forestalling the cellular senescence, apoptosis, and genomic instability that result from telomere loss caused by incomplete DNA replication. The telomerase ribonucleoprotein is dedicated to synthesis of tandem, simple-sequence repeats by virt...

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Bibliografiske detaljer
Main Authors: Miller, Michael C., Collins, Kathleen
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC124446/
https://ncbi.nlm.nih.gov/pubmed/11997465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102024699
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