Telomerase recognizes its template by using an adjacent RNA motif

Telomerase adds telomeric repeats to chromosome 3′ ends, forestalling the cellular senescence, apoptosis, and genomic instability that result from telomere loss caused by incomplete DNA replication. The telomerase ribonucleoprotein is dedicated to synthesis of tandem, simple-sequence repeats by virt...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Miller, Michael C., Collins, Kathleen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124446/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997465/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.102024699
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