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A mouse model for nonsense mutation bypass therapy shows a dramatic multiday response to geneticin
Aminoglycosides can bypass nonsense mutations and are the prototypic agents for translational bypass therapy (TBT). Initial results demonstrate the need for more potent drugs and an in vivo model system for quantitative assessment of TBT. Herein, we present an in vivo system for evaluating the effic...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000501/ https://ncbi.nlm.nih.gov/pubmed/17881586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610878104 |
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