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Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium
Proteins are involved in various equilibria that play a major role in their activity or regulation. The design of molecules that shift such equilibria is of great therapeutic potential. This fact was demonstrated in the cases of allosteric inhibitors, which shift the equilibrium between active and i...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895947/ https://ncbi.nlm.nih.gov/pubmed/17488811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700781104 |
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