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Nucleocytoplasmic shuttling of HIV-1 integrase is controlled by the viral Rev protein

In the current study we show that the Rev protein of Human Immunodeficiency Virus type 1 (HIV-1) inhibits nuclear import and mediates nuclear export of the HIV-1 integrase (IN) protein, which catalyzes integration of the viral cDNA. Interaction between IN and Rev in virus infected cells, resulting i...

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Bibliografski detalji
Glavni autori: Levin, Aviad, Hayouka, Zvi, Friedler, Assaf, Loyter, Abraham
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030695/
https://ncbi.nlm.nih.gov/pubmed/21326951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.1.2.11300
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