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Nucleocytoplasmic shuttling of HIV-1 integrase is controlled by the viral Rev protein
In the current study we show that the Rev protein of Human Immunodeficiency Virus type 1 (HIV-1) inhibits nuclear import and mediates nuclear export of the HIV-1 integrase (IN) protein, which catalyzes integration of the viral cDNA. Interaction between IN and Rev in virus infected cells, resulting i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3030695/ https://ncbi.nlm.nih.gov/pubmed/21326951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.1.2.11300 |
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