Antimyeloma activity of heat shock protein-90 inhibition

We show that multiple myeloma (MM), the second most commonly diagnosed hematologic malignancy, is responsive to hsp90 inhibitors in vitro and in a clinically relevant orthotopic in vivo model, even though this disease does not depend on HER2/neu, bcr/abl, androgen or estrogen receptors, or other hsp...

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Detaylı Bibliyografya
Asıl Yazarlar: Mitsiades, Constantine S., Mitsiades, Nicholas S., McMullan, Ciaran J., Poulaki, Vassiliki, Kung, Andrew L., Davies, Faith E., Morgan, Gareth, Akiyama, Masaharu, Shringarpure, Reshma, Munshi, Nikhil C., Richardson, Paul G., Hideshima, Teru, Chauhan, Dharminder, Gu, Xuesong, Bailey, Charles, Joseph, Marie, Libermann, Towia A., Rosen, Neal S., Anderson, Kenneth C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: © 2006 by The American Society of Hematology 2006
Konular:
Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895907/
https://ncbi.nlm.nih.gov/pubmed/16234364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1158
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