Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells

CREB-binding protein (CBP) and its para-log p300 are transcriptional coactivators that physically or functionally interact with over 320 mammalian and viral proteins, including 36 that are essential for B cells in mice. CBP and p300 are generally considered limiting for transcription, yet their role...

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Detalhes bibliográficos
Main Authors: Xu, Wu, Fukuyama, Tomofusa, Ney, Paul A., Wang, Demin, Rehg, Jerold, Boyd, Kelli, van Deursen, Jan M. A., Brindle, Paul K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895794/
https://ncbi.nlm.nih.gov/pubmed/16424387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3263
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