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Plasminogen inhibits TNFα-induced apoptosis in monocytes

Monocytes are major mediators of inflammation, and apoptosis provides a mechanism for regulating the inflammatory response by eliminating activated macrophages. Furthermore, as a consequence of apoptosis, plasminogen binding is markedly increased on monocytoid cells. Therefore, we investigated the a...

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Bibliografiske detaljer
Main Authors: Mitchell, Jennifer W., Baik, Nagyung, Castellino, Francis J., Miles, Lindsey A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Hematology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895791/
https://ncbi.nlm.nih.gov/pubmed/16478887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2872
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