Tumor necrosis factor α (TNF-α) receptor-II is required for TNF-α–induced leukocyte-endothelial interaction in vivo

Tumor necrosis factor-α (TNF-α) binds to 2 distinct cell-surface receptors: TNF-α receptor-I (TNFR-I: p55) and TNF-α receptor-II (TNFR-II: p75). TNF-α induces leukocyte adhesion molecules on endothelial cells (ECs), which mediate 3 defined steps of the inflammatory response; namely, leukocyte rollin...

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Autors principals: Chandrasekharan, Unni M., Siemionow, Maria, Unsal, Murat, Yang, Lin, Poptic, Earl, Bohn, Justin, Ozer, Kagan, Zhou, Zhongmin, Howe, Philip H., Penn, Marc, DiCorleto, Paul E.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2007
Matèries:
Hemostasis, Thrombosis, and Vascular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801063/
https://ncbi.nlm.nih.gov/pubmed/17068152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-05-020875
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