Monoclonal antibodies detect receptor-induced binding sites in Glu-plasminogen

When Glu-plasminogen binds to cells, its activation to plasmin is markedly enhanced compared with the reaction in solution, suggesting that Glu-plasminogen on cell surfaces adopts a conformation distinct from that in solution. However, direct evidence for such conformational changes has not been obt...

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Detalhes bibliográficos
Main Authors: Han, Jaena, Baik, Nagyung, Kim, Kee-Hwan, Yang, Jian-Ming, Han, Gye Won, Gong, Yun, Jardí, Mercè, Castellino, Francis J., Felez, Jordi, Parmer, Robert J., Miles, Lindsey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156051/
https://ncbi.nlm.nih.gov/pubmed/21680799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-316943
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