Monoclonal antibodies against receptor-induced binding sites detect cell-bound plasminogen in blood

Binding of Glu-plasminogen (the native, circulating form of the zymogen) to cells results in enhancement of its activation. Cell-associated plasmin proteolytic activity is a key component of physiologic and pathologic processes requiring extracellular matrix degradation. Recently, we developed antip...

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Bibliographic Details
Main Authors: Félez, Jordi, Jardí, Mercè, Fàbregas, Pere, Parmer, Robert J., Miles, Lindsey A.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2012
Subjects:
Thrombosis and Hemostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401219/
https://ncbi.nlm.nih.gov/pubmed/22649107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-410480
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