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The anti-fibrinolytic SERPIN, plasminogen activator inhibitor 1 (PAI-1), is targeted to and released from catecholamine storage vesicles

Recent studies suggest a crucial role for plasminogen activator inhibitor-1 (PAI-1) in mediating stress-induced hypercoagulability and thrombosis. However, the mechanisms by which PAI-1 is released by stress are not well-delineated. Here, we examined catecholaminergic neurosecretory cells for expres...

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Detalhes bibliográficos
Main Authors: Jiang, Qijiao, Gingles, Neill A., Olivier, Marc A., Miles, Lindsey A., Parmer, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143556/
https://ncbi.nlm.nih.gov/pubmed/21596853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-287672
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