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A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation
Altered mRNA translation is one of the effects exerted by the BCR/ABL oncoprotein in the blast crisis phase of chronic myelogenous leukemia (CML). Here, we report that in BCR/ABL(+) cell lines and in patient-derived CML blast crisis mononuclear and CD34(+) cells, p210(BCR/ABL) increases expression a...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society of Hematology
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895740/ https://ncbi.nlm.nih.gov/pubmed/16293596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3732 |
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