Expansion of HIV-specific CD4(+) and CD8(+) T cells by dendritic cells transfected with mRNA encoding cytoplasm- or lysosome-targeted Nef

Transfection with synthetic mRNA is a safe and efficient method of delivering antigens to dendritic cells for immunotherapy. Targeting antigens to the lysosome can sometimes enhance the CD4(+) T-cell response. We transfected antigen-presenting cells (APCs) with mRNA encoding Gag-p24 and cytoplasmic,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kavanagh, Daniel G., Kaufmann, Daniel E., Sunderji, Sherzana, Frahm, Nicole, Le Gall, Sylvie, Boczkowski, David, Rosenberg, Eric S., Stone, David R., Johnston, Mary N., Wagner, Bradford S., Zaman, Mohammad T., Brander, Christian, Gilboa, Eli, Walker, Bruce D., Bhardwaj, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895708/
https://ncbi.nlm.nih.gov/pubmed/16249391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-04-1513
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados