Induction of Tumor-Specific Cytotoxic T Lymphocytes in Cancer Patients by Autologous Tumor RNA-Transfected Dendritic Cells

OBJECTIVE: To demonstrate the feasibility of inducing tumor antigen-specific immune responses in patients with metastatic cancer using total tumor RNA-loaded dendritic cells (DCs). SUMMARY BACKGROUND DATA: The authors have shown that DCs transfected with mRNA encoding defined tumor antigens induce t...

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Detalhes bibliográficos
Main Authors: Nair, Smita K., Morse, Michael, Boczkowski, David, Ian Cumming, R., Vasovic, Ljiljana, Gilboa, Eli, Kim Lyerly, H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422470/
https://ncbi.nlm.nih.gov/pubmed/11923611
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