Human Tumor–infiltrating Lymphocytes Transfected with Tumor Necrosis Factor Gene Could Augment Cytotoxicity to Autologous Tumor Cells

Human tumor–infiltrating lymphocytes (TILs) derived from pleural or ascitic fluid were incubated with recombinant interleukin 2 and transfected with human tumor necrosis factor (TNF) a gene by the lipofection procedure. The resulting TILs secreted significant amounts of TNF in the culture supernatan...

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Détails bibliographiques
Publié dans:Jpn J Cancer Res
Auteurs principaux: Itoh, Yoshinori, Kohgo, Yutaka, Watanabe, Naoki, Kanisawa, Yuji, Sakamaki, Sumio, Takahashi, Minoru, Hirayama, Yasuo, Ono, Hiroyuki, Himeno, Takeshi, Niitsu, Yoshiro
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 1991
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918323/
https://ncbi.nlm.nih.gov/pubmed/1752779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01781.x
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