Human Tumor–infiltrating Lymphocytes Transfected with Tumor Necrosis Factor Gene Could Augment Cytotoxicity to Autologous Tumor Cells

Human tumor–infiltrating lymphocytes (TILs) derived from pleural or ascitic fluid were incubated with recombinant interleukin 2 and transfected with human tumor necrosis factor (TNF) a gene by the lipofection procedure. The resulting TILs secreted significant amounts of TNF in the culture supernatan...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Itoh, Yoshinori, Kohgo, Yutaka, Watanabe, Naoki, Kanisawa, Yuji, Sakamaki, Sumio, Takahashi, Minoru, Hirayama, Yasuo, Ono, Hiroyuki, Himeno, Takeshi, Niitsu, Yoshiro
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1991
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918323/
https://ncbi.nlm.nih.gov/pubmed/1752779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01781.x
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