Human Tumor–infiltrating Lymphocytes Transfected with Tumor Necrosis Factor Gene Could Augment Cytotoxicity to Autologous Tumor Cells

Human tumor–infiltrating lymphocytes (TILs) derived from pleural or ascitic fluid were incubated with recombinant interleukin 2 and transfected with human tumor necrosis factor (TNF) a gene by the lipofection procedure. The resulting TILs secreted significant amounts of TNF in the culture supernatan...

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Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Itoh, Yoshinori, Kohgo, Yutaka, Watanabe, Naoki, Kanisawa, Yuji, Sakamaki, Sumio, Takahashi, Minoru, Hirayama, Yasuo, Ono, Hiroyuki, Himeno, Takeshi, Niitsu, Yoshiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 1991
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918323/
https://ncbi.nlm.nih.gov/pubmed/1752779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01781.x
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