Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors

Autologous dendritic cells (DCs) transfected with mRNA encoding prostate-specific antigen (PSA) are able to stimulate potent, T cell–mediated antitumor immune responses in vitro. A phase I trial was performed to evaluate this strategy for safety, feasibility, and efficacy to induce T cell responses...

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Detalhes bibliográficos
Main Authors: Heiser, Axel, Coleman, Doris, Dannull, Jens, Yancey, Donna, Maurice, Margaret A., Lallas, Costas D., Dahm, Philipp, Niedzwiecki, Donna, Gilboa, Eli, Vieweg, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150859/
https://ncbi.nlm.nih.gov/pubmed/11828001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14364
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