Comprehensive Analysis of Human Immunodeficiency Virus Type 1-Specific CD4 Responses Reveals Marked Immunodominance of gag and nef and the Presence of Broadly Recognized Peptides

Increasing evidence suggests that human immunodeficiency virus type 1 (HIV-1)-specific CD4 T-cell responses contribute to effective immune control of HIV-1 infection. However, the breadths and specificities of these responses have not been defined. We screened fresh CD8-depleted peripheral blood mon...

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Autori principali: Kaufmann, Daniel E., Bailey, Paul M., Sidney, John, Wagner, Bradford, Norris, Philip J., Johnston, Mary N., Cosimi, Lisa A., Addo, Marylyn M., Lichterfeld, Mathias, Altfeld, Marcus, Frahm, Nicole, Brander, Christian, Sette, Alessandro, Walker, Bruce D., Rosenberg, Eric S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC387674/
https://ncbi.nlm.nih.gov/pubmed/15078927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4463-4477.2004
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