AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation

AKT serine threonine kinase of the protein kinase B (PKB) family plays essential roles in cell survival, growth, metabolism, and differentiation. In the erythroid system, AKT is known to be rapidly phosphorylated and activated in response to erythropoietin (Epo) engagement of Epo receptor (EpoR) and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ghaffari, Saghi, Kitidis, Claire, Zhao, Wei, Marinkovic, Dragan, Fleming, Mark D., Luo, Biao, Marszalek, Joseph, Lodish, Harvey F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: © 2006 by The American Society of Hematology 2006
Pynciau:
Hematopoiesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895702/
https://ncbi.nlm.nih.gov/pubmed/16254141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2304
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg