Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway

Erythropoietin (Epo) stimulation of its receptor's downstream signaling pathways and optimum function of GATA-1 transcription factor are both essential for normal erythroid cell development. Epo-receptor (EpoR) signaling and GATA-1 regulate proliferation, survival, differentiation, and maturati...

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Detalhes bibliográficos
Main Authors: Zhao, Wei, Kitidis, Claire, Fleming, Mark D., Lodish, Harvey F., Ghaffari, Saghi
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Hematopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895894/
https://ncbi.nlm.nih.gov/pubmed/16204311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2516
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