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Activating Notch1 mutations in mouse models of T-ALL
Recent studies have demonstrated that most patients with T-cell acute lymphocytic leukemia (T-ALL) have activating mutations in NOTCH1. We sought to determine whether these mutations are also acquired in mouse models of T-ALL. We sequenced the heterodimerization domain and the PEST domain of Notch1...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society of Hematology
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895623/ https://ncbi.nlm.nih.gov/pubmed/16166587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2553 |
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