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Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines
The fate of tumor-specific CD4(+) T cells is central to the outcome of the host immune response to cancer. We show that tumor antigen recognition by a subset of CD4(+) T cells led to their differentiation into cells capable of suppressing naive and Th1 effector cells. Such tumor-induced regulatory T...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society of Hematology
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895618/ https://ncbi.nlm.nih.gov/pubmed/16179369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2737 |
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