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Escape from suppression: tumor-specific effector cells outcompete regulatory T cells following stem-cell transplantation
Immune reconstitution of autologous hematopoietic stem-cell transplant recipients with the progeny of mature T cells in the graft leads to profound changes in the emerging functional T-cell repertoire. In the steady state, the host is frequently tolerant to tumor antigens, reflecting dominant suppre...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234051/ https://ncbi.nlm.nih.gov/pubmed/18063750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-096586 |
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