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Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines

The fate of tumor-specific CD4(+) T cells is central to the outcome of the host immune response to cancer. We show that tumor antigen recognition by a subset of CD4(+) T cells led to their differentiation into cells capable of suppressing naive and Th1 effector cells. Such tumor-induced regulatory T...

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Detalhes bibliográficos
Main Authors: Zhou, Gang, Drake, Charles G., Levitsky, Hyam I.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895618/
https://ncbi.nlm.nih.gov/pubmed/16179369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2737
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