Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation

Local vasodilation in response to hypoxia is a fundamental physiologic response ensuring oxygen delivery to tissues under metabolic stress. Recent studies identify a role for the red blood cell (RBC), with hemoglobin the hypoxic sensor. Herein, we investigate the mechanisms regulating this process a...

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Detalhes bibliográficos
Main Authors: Crawford, Jack H., Isbell, T. Scott, Huang, Zhi, Shiva, Sruti, Chacko, Balu K., Schechter, Alan N., Darley-Usmar, Victor M., Kerby, Jeffrey D., Lang, John D., Kraus, David, Ho, Chien, Gladwin, Mark T., Patel, Rakesh P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895612/
https://ncbi.nlm.nih.gov/pubmed/16195332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2668
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