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Simultaneous activation of multiple signal transduction pathways confers poor prognosis in acute myelogenous leukemia

Deregulation of signal transduction pathways (STPs) may promote leukemogenesis by conferring cell proliferation and survival advantages in acute myelogenous leukemia (AML). Several agents targeting STPs are under development; however, redundancy and cross-talk between STPs could activate multiple do...

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Detalhes bibliográficos
Main Authors: Kornblau, Steven M., Womble, Matthew, Qiu, Yi Hua, Jackson, C. Ellen, Chen, Wenjing, Konopleva, Marina, Estey, Elihu H., Andreeff, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895551/
https://ncbi.nlm.nih.gov/pubmed/16763210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-003475
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